Acute Myocardial Infarction (AMI) |
- Chest pain or discomfort, often described as pressure, tightness, or squeezing, radiating to the arm, neck, jaw, or back.
- Shortness of breath, diaphoresis (sweating), nausea, and lightheadedness.
- Symptoms may be atypical in women, elderly patients, and those with diabetes.
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- Electrocardiogram (ECG) showing ST-segment elevation, T-wave inversion, or new left bundle branch block.
- Serum cardiac biomarkers (troponin, CK-MB) elevated.
- Chest X-ray to rule out other causes of chest pain.
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- Immediate administration of aspirin, nitrates, and oxygen if hypoxic.
- Reperfusion therapy: Primary percutaneous coronary intervention (PCI) is preferred; thrombolytic therapy if PCI is not available.
- Beta-blockers, ACE inhibitors, and statins as part of long-term management.
- Anticoagulation with heparin or enoxaparin during acute management.
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Cardiac Tamponade |
- Beck's triad: Hypotension, muffled heart sounds, and jugular venous distension (JVD).
- Tachycardia, pulsus paradoxus (a drop in systolic BP >10 mm Hg during inspiration), and dyspnoea.
- May follow trauma, malignancy, pericarditis, or myocardial rupture.
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- Echocardiography showing pericardial effusion with signs of tamponade (e.g., right atrial or ventricular diastolic collapse).
- ECG may show low voltage QRS complexes or electrical alternans.
- Chest X-ray showing an enlarged cardiac silhouette (water-bottle heart) in chronic cases.
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- Urgent pericardiocentesis to remove fluid from the pericardial sac.
- Volume expansion with IV fluids to increase cardiac output.
- Treatment of the underlying cause (e.g., pericarditis, malignancy).
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Aortic Dissection |
- Sudden onset of severe, tearing chest or back pain, often radiating to the neck or abdomen.
- Asymmetry in blood pressure between arms, pulse deficits, and possible signs of shock.
- History of hypertension, connective tissue disorders, or bicuspid aortic valve.
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- CT angiography of the chest and abdomen showing the dissection flap and extent of the dissection.
- Transesophageal echocardiography (TEE) or MRI if CT is not available.
- Chest X-ray may show a widened mediastinum.
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- Immediate blood pressure control with IV beta-blockers (e.g., esmolol) and vasodilators (e.g., nitroprusside).
- Urgent surgical repair for type A dissections (involving the ascending aorta).
- Medical management and close monitoring for type B dissections (descending aorta) without complications.
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Pulmonary Embolism (PE) |
- Sudden onset of pleuritic chest pain, shortness of breath, and hemoptysis.
- Tachypnea, tachycardia, hypoxia, and signs of deep vein thrombosis (DVT) such as leg swelling or pain.
- Possible syncope or shock in massive PE.
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- CT pulmonary angiography (CTPA) showing filling defects in the pulmonary arteries.
- D-dimer test to rule out PE in low-risk patients.
- ECG may show sinus tachycardia, right heart strain (e.g., S1Q3T3 pattern).
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- Immediate anticoagulation with IV heparin or low-molecular-weight heparin (LMWH).
- Thrombolytic therapy for massive PE with hemodynamic instability.
- Consider surgical embolectomy or catheter-directed thrombolysis in severe cases.
- Long-term anticoagulation and investigation for underlying causes (e.g., malignancy, thrombophilia).
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Ventricular Tachycardia (VT) |
- Palpitations, dizziness, syncope, or sudden cardiac arrest.
- Rapid, regular heart rate (usually >150 bpm) with wide QRS complexes on ECG.
- May occur in patients with underlying heart disease, electrolyte imbalances, or after an MI.
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- ECG showing wide QRS complex tachycardia.
- Serum electrolytes to check for abnormalities (e.g., hypokalemia, hypomagnesemia).
- Echocardiography or cardiac MRI to assess underlying structural heart disease.
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- If unstable, immediate synchronized cardioversion.
- If stable, antiarrhythmic medications (e.g., amiodarone, lidocaine) may be used.
- Correction of underlying electrolyte imbalances.
- Consideration of implantable cardioverter-defibrillator (ICD) in patients at high risk of recurrence.
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Acute Heart Failure / Pulmonary Edema |
- Severe shortness of breath, orthopnea, and paroxysmal nocturnal dyspnoea.
- Crackles on lung auscultation, frothy sputum, and signs of fluid overload (e.g., peripheral edema, JVD).
- Tachycardia, hypotension, and possible cyanosis in severe cases.
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- Chest X-ray showing pulmonary congestion, interstitial edema, and possibly pleural effusions.
- BNP or NT-proBNP levels elevated, indicating heart failure.
- Echocardiography to assess ejection fraction and rule out structural abnormalities.
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- Immediate administration of IV diuretics (e.g., furosemide) to reduce fluid overload.
- Oxygen therapy or non-invasive ventilation (CPAP/BiPAP) for respiratory distress.
- Vasodilators (e.g., nitroglycerin) to reduce preload and afterload.
- Inotropic support (e.g., dobutamine) for patients with cardiogenic shock.
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Hypertensive Emergency |
- Severe hypertension (typically >180/120 mm Hg) with evidence of end-organ damage.
- Symptoms may include chest pain, headache, visual changes, dyspnoea, or neurological deficits.
- May lead to complications such as stroke, myocardial infarction, or acute kidney injury.
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- Blood pressure measurement confirming severe hypertension.
- ECG, urinalysis, and blood tests (e.g., creatinine) to assess for end-organ damage.
- Head CT or MRI if neurological symptoms are present.
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- Immediate IV antihypertensive agents (e.g., labetalol, nitroprusside, nicardipine) to gradually reduce blood pressure.
- Monitoring in an ICU setting with continuous blood pressure monitoring.
- Treatment of the underlying cause (e.g., pheochromocytoma, renal artery stenosis).
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Bradycardia with Hemodynamic Instability |
- Heart rate <60 bpm with signs of decreased perfusion (e.g., hypotension, altered mental status, chest pain).
- May be caused by sinus node dysfunction, AV block, or drug overdose.
- Symptoms include dizziness, syncope, fatigue, and shortness of breath.
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- ECG showing bradycardia and possible heart block.
- Serum electrolytes to rule out hyperkalemia or other metabolic causes.
- Drug levels if overdose is suspected (e.g., beta-blockers, digoxin).
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- Immediate administration of atropine IV; if ineffective, consider transcutaneous pacing.
- Dopamine or epinephrine infusion if bradycardia persists and pacing is not immediately available.
- Identify and treat the underlying cause (e.g. stop offending medications, correct electrolyte imbalances).
- Permanent pacemaker may be required for persistent symptomatic bradycardia.
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Acute Coronary Syndrome (ACS) - Unstable Angina/NSTEMI |
- Chest pain or discomfort that is new, occurs at rest, or is worsening in frequency or intensity.
- May be associated with shortness of breath, diaphoresis, nausea, and lightheadedness.
- Symptoms may be atypical in women, elderly patients, and those with diabetes.
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- ECG showing ST-segment depression or T-wave inversion; may be normal in some cases.
- Serum cardiac biomarkers (troponin) may be elevated in NSTEMI, but not in unstable angina.
- Chest X-ray to rule out other causes of chest pain.
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- Immediate administration of aspirin, nitrates, and oxygen if hypoxic.
- Anticoagulation with heparin or enoxaparin, and dual antiplatelet therapy (e.g., aspirin and clopidogrel).
- Beta-blockers and statins as part of long-term management.
- Consideration of early invasive strategy (e.g., coronary angiography) in high-risk patients.
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