Related Subjects:
|Drug Toxicity - clinical assessment
|Metabolic acidosis
|Aspirin or Salicylates toxicity
|Ethylene glycol toxicity
|Ethanol toxicity
|Methanol toxicity
|Ricin toxicity
|Carbon Tetrachloride Toxicity
|Renal Tubular Acidosis
|Lactic acidosis
|Iron Toxicity
|Tricyclic Antidepressant Toxicity
|Opiate Toxicity
|Carbon monoxide Toxicity
|Benzodiazepine Toxicity
|Paracetamol (Acetaminophen) toxicity
|Amphetamine toxicity
|Beta Blocker toxicity
|Calcium channel blockers toxicity
|Cannabis toxicity
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|Digoxin Toxicity
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|Drug Toxicity with Specific Antidotes
Deaths or episodes of acute liver failure in patients who start treatment
within 8 hours (h) of a single acute overdose are extremely rare because of the
ease of availability of a highly effective antidote, acetylcysteine
Treatment line: Treat all above the line
A ceiling weight of 110 kg should be used when calculating the dose for obese patients. NAC is virtually 100% effective in preventing liver damage when given within 8 hours of the overdose
Give Bag 4 if any of the following
About
Metabolism: Toxicity from NADPQI
Aetiology
Clinical
Investigations
Management:When to start NAC: N-Acetylcysteine
Management:When to give Activated charcoal
Giving NAC
Side effects of NAC
Monitor
Criteria for Transfer to Liver Unit
Poor Prognosis
References
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Paracetamol (Acetaminophen) toxicity
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