PT result APTT result Common condition present
Prolonged
Normal
Liver disease, decreased Vitamin K, decreased or defective factor VII
Normal
Prolonged
Hemophilia A or B (decreased or defective factor VIII or IX) or factor XI deficiency, von Willebrand disease, factor XII deficiency, or lupus anticoagulant present
Prolonged
Prolonged
Decreased or defective factor I (fibrinogen), II (prothrombin), V or X, severe liver disease, disseminated intravascular coagulation (DIC)
Normal
Normal or slightly prolonged
May indicate normal haemostasis; however, PT and PTT can be normal in conditions such as mild deficiencies in other factors and mild form of von Willebrand disease. Further testing may be required to diagnose these conditions.
Prothrombin time
Prolonged Prothrombin time
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Prothrombin time and Coagulation
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