Makindo Medical Notes.com

Adrenal steroids

• Serum aldosterone (normal diet) : Upright (4h) 330 - 830 pmol/L, Supine (30m) 135 - 400 pmol/L
• Serum cortisol: 09.00h 200 - 700 nmol/L, 22.00h 50 - 250 nmol/L
• Overnight dexamethasone suppression test (after 1mg dexamethasone) : Serum cortisol < 50 nmol/l
• Low dose dexamethasone suppression test (2 mg/day for 48h) Serum cortisol < 50 nmol/L
• After Insulin-induced hypoglycaemia (blood glucose < 2.2 mmol/L) Serum cortisol > 550 nmol/L and 200 nmol/L greater than baseline
• Plasma 11 - deoxycortisol 24 - 46 nmol/L
• Serum dehydroepiandrosterone (09.00) 7 - 31 nmol/L
• Serum dehydroepiandrosterone sulphate: (Males) 2 - 10 mol/L, (Females) 3 - 12 micromol/L
• Serum androstenedione (adults) Males 1.6 - 8.4 nmol/L, Females 0.6 - 8.8 nmol/L, Post menopausal females 0.9 - 6.8 nmol/L
• Serum 17-hydroxyprogesterone: Males 1 - 10 nmol/L, Females Follicular 1 - 10 nmol/L, Luteal 10 - 20 nmol/L
• Serum oestradiol Males < 180 pmol/L, Females Post-menopausal < 100 pmol/L, Follicular 200 - 400 pmol/L, Mid-cycle 400 - 1200 pmol/L, Luteal 400 - 1000 pmol/L
• Serum progesterone: Males < 6 nmol/L, Females Follicular < 10 nmol/L, Luteal > 30 nmol/L,
• Serum testosterone: Males 9 - 35 nmol/L, Females 0.5 - 3 nmol/L
• Serum dihydrotestosterone, Males 1- 2.6 nmol/L, Females 0.3 - 9.3 nmol/L
• Serum sex hormone binding protein: Males 10 - 62 nmol/L, Females 40 - 137 nmol/L,

Urine

• Aldosterone 14 - 53 nmol/24h
• Cortisol 55 - 250 nmol/24h
• Plasma angiotensin II 5 - 35 pmol/L
• Plasma renin activity Recumbent 1.1 - 2.7 pmol/ml/h, Erect after 30m 3.0 - 4.3 pmol/ml/h

Pancreatic and gut hormones

• Plasma gastrin < 55 pmol/L
• Plasma or serum Insulin: Overnight fasting < 186 pmol/L, After hypoglycaemia (Blood glucose < 2.2 mmol/L) < 21 pmol/L
• Plasma vasoactive intestinal polypeptide < 30 pmol/L
• Plasma pancreatic polypeptide < 300 pmol/L
• Plasma glucagon < 50 pmol/L

Anterior pituitary hormones

• Plasma adrenocorticotrophic hormone 09.00 < 18 pmol/L
• Plasma follicle stimulating hormone Males 1 - 7 U/L Females Follicular 2.5 - 10 U/L, Midcycle 25 - 70 U/L, Luteal 0.32 - 2.1 U/L, Post-menopausal > 30 U/L
• Plasma growth hormone: Basal, fasting and between pulses < 1 mU/L, After hypoglycaemia > 40 mU/L,
• Plasma luteinizing hormone Males 1 - 10 U/L, Females Follicular 2.5 - 10 U/L, Midcycle 25 - 70 U/L, Luteal 1 - 13 U/L, Post-menopausal > 30 U/L,
• Plasma prolactin < 360 mU/L or
• Serum prolactin < 20 ng/mL or 20 μg/L
• Plasma thyroid-stimulating hormone 0.4 - 5 mU/L

Posterior pituitary hormones

• Plasma antidiuretic hormone 0.9 - 4.6 pmol/L

Thyroid hormones

• Plasma thyroid binding globulin 13 - 28 mg/L
• Plasma thyroxine (T4) 58 - 174 nmol/L
• Free T4 10 - 22 pmol/L
• Tri-iodothyronine (T3) 1.07 - 3.18 nmol/L
• Free T3 5 - 10 pmol/L
• Serum TSH receptor antibodies < 7 U/L
• Serum antithyroid peroxidase < 50 IU/mL
• Serum thyroid receptor antibodies < 10 U/L

Catecholamines

(Plasma recumbent with venous catheter in place for 30m prior to collection of sample)
• Adrenaline 0.03 - 1.31 nmol/L
• Noradrenaline 0.47 - 4.14 nmol/L

Urine

• Vanillyl mandelic acid 5 - 35 micromol/24h
• Dopamine < 3100 nmol/24h
• Adrenaline < 144 nmol/24h
• Noradrenaline < 570 nmol/24h
• Hydroxyindole acetic acid < 70 micromol/24h

Others

• Plasma parathyroid hormone 0.9 - 5.4 pmol/L
• Plasma calcitonin < 27 pmol/L
• Serum cholecalciferol (vitamin D3) 60 - 105 nmol/L
• Serum 25 - OH - cholecalciferol 45 - 90 nmol/L
• Age-related Insulin like growth factor - 1 : 13 - 15 yrs 9.3 - 56.0 nmol/L, 16 - 18 yrs 9.3 - 56.0 nmol/L, 20 - 40 yrs 7.5 - 37.3 nmol/L, 40 - 60 yrs 5.6 - 23.3 nmol/L, >60 yrs 3.3 - 23.3 nmol/L