|Sedation and Analgesia on ITU
- Check BNF or equivalent for UpToDate prescribing advice
Mode of action
- a semi-synthetic opioid analgesic prescribed for pain or severe dyspnoea, or as an antitussive
- Given either alone or with paracetamol
- Dihydrocodeine 30 mg every 4 to 6 hours when necessary.
- Maximum 240 mg in 24 hours.
- Avoid with sedatives and alcohol
- Respiratory depression may need ventilation/naloxone
- Acute respiratory depression; comatose patients; head injury
- Raised ICP, paralytic ileus
- Drowsy, Arrhythmias, delirium and confusion; constipation; dizziness
- Dry mouth; euphoric mood; flushing; hallucination; headache; hyperhidrosis; hypotension (with high doses)
- Miosis, nausea/vomiting, respiratory depression (with high doses); skin reactions; urinary retention
- Vertigo; visual impairment; withdrawal syndrome