Makindo Medical Notes.com |
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The Vaughan-Williams Classification is still useful
Class | Action | Drug |
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Class Ia | Prolong Action Potential duration | Disopyramide, Propafenone, Procainamide |
Class Ib | Shortens Action Potential duration | Lidocaine, mexiletine, tocainide |
Class Ic | Normal Action Potential duration and prolongs QT | Flecainide |
Class II | Beta Blockers | Beta blockers |
Class III | Prolongs QT | Sotalol and Amiodarone - can lead to torsade de pointes especially in those with hypokalaemia. Dofetilide has been used to treat AF |
Class IV | Calcium channel blockers | Verapamil and Diltiazem |