Do not confuse the doses of hyoscine butylbromide with the much lower dose of hyoscine hydrobromide.
About: Always check the BNF links below or equivalent for prescribing advice
- Blurred vision may affect driving
Mode of action
- Antimuscarinics (anticholinergic)
- Hyoscine butylbromide is less sedative than hyoscine hydrobromide.
- Bowel spasms, Colic, Excess respiratory secretions: Hyoscine butylbromide (Buscopan) 20 mg 4 times daily
- Irritable bowel syndrome, Hyoscine butylbromide (Buscopan) 10-20 mg 3-4 times daily,
- Acute spasm: Hyoscine butylbromide (Buscopan) 20 mg IM or slow IV repeated after 30 minutes if necessary
- Excess Secretions palliative: s/c infusion dose of 20-120 mg/24 hours
- Bowel colic palliation: s/c infusion dose of 60-300 mg/24 hours
- Hyoscine hydrobromide effectively reduces respiratory secretions and bowel colic
- It is a sedative (but occasionally causes paradoxical agitation).
- It is given in a subcutaneous infusion dose of 1.2-2 mg/24 hours.
- Excess secretions palliative: Hyoscine hydrobromide 1.2-2 mg/24 hours.
- Bowel colic palliative: Hyoscine hydrobromide 1.2-2 mg/24 hours.
- Tachycardic, thyrotoxic, prostatism
- Myasthenia gravis, closed-angle glaucoma
- Caution in pregnancy - seek advice
- See Antimuscarinics
- Reduced secretions - dry mouth, Sedation
- Pupils dilate - blurred vision
Increased heart rate, Relax smooth bowel
- Urinary retention, Reduced ability to sweat.
- Allergic skin reactions. See Antimuscarinics