Side effects can be severe so long term treatment is specialist initiated for life-threatening arrhythmias or where there is no alternative. Amiodarone is a very useful antiarrhythmic that possesses class III properties. It is irritant and extravasation can be serious. Patients should be fully counselled regarding the risks of long term Amiodarone therapy.
About : Always check the BNF link here
Mode of action
Pharmacokinetics
Indications
Contraindications
Side effects
Interactions
Dose range:You must check with BNF or drug datasheet
Name Starting Dose Frequency Route Amiodarone (Cardiac arrest) 300 mg stat IV in 20 - 30 ml of NS or D5W usually after 3rd shock. Amiodarone (Arrhythmias) 150-300 mg stat Slow IV in 250 ml 5% dextrose over 30-60 mins Amiodarone (Arrhythmias Loading IV) 900 mg over 24 hours Slow IV in 250 ml 5% dextrose over 24 hours in 500 ml 5% Dextrose by central line Amiodarone (Oral loading) 200 mg OD PO. oral loading 200 mg TDS for one week then BD for a week then OD Dose
References
MEDICAL DISCLAIMER:The contents are under continuing development and improvements and despite all efforts may contain errors of omission or fact. This is not to be used for the assessment, diagnosis or management of patients. It should not be regarded as medical advice by healthcare workers or laypeople. It is for educational purposes only. Please adhere to your local protocols. Use the BNF for drug information. If you are unwell please seek urgent healthcare advice. If you do not accept this then please do not use the website. Makindo Ltd |
Amiodarone
-
| About | Anaesthetics and Critical Care | Anatomy | Basic Science | Biochemistry | Cardiology | Cases | Clinical Cases | Crib | Dentistry | Dermatology | Differentials | Drugs | ENT | Electrocardiogram | Embryology | Emergency Medicine | Endocrinology | Ethics | Foundation Doctors | Gastroenterology | General Information | General Practice | Genetics | Geriatric Medicine | Guidelines | Haematology | Hepatology | Immunology | Infectious Disease | Infectious Diseases | Infographic | Investigations | Lists | Microbiology | Miscellaneous | Nephrology | Neuroanatomy | Neurology | Nutrition | OSCE | Obstetrics Gynaecology | Oncology | Ophthalmology | Oral Medicine | Paediatrics | Palliative | Pathology | Pharmacology | Physiology | Procedures | Psychiatry | Radiology | Research | Respiratory | Resuscitation | Rheumatology | Statistics | Stroke | Surgery | Surgical | Toxicology | Trauma and Orthopaedics | Twitter | Urology | Version Jan 2023