Be very cautious with combinations of these drugs
About: Always check the BNF link here
Drugs to Avoid in Renal failure
Drugs Details
ACEI/AT2 Blockers Can reduce GFR and cause raised K and worsening function Aminoglycosides e.g. Gentamicin Nephrotoxic Opiates/Codeine Increased toxicity and sedation Lithium Lithium toxicity and arrhythmias and seizures Diuretics Can worsen dehydration and renal function Erythromycin Encephalopathy Penicilln/Cephalopsorin High dose causes Encephalopathy Amphotericin B Nephrotoxic Ciclosporin A Nephrotoxic Aciclovir Nephrotoxic. Ensure well hydrated Methotrexate Nephrotoxic Tacrolimus Nephrotoxic NSAIDS Nephrotoxic
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Drugs to Avoid in Acute Renal failure
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