- Check BNF or equivalent for UpToDate prescribing advice
Mode of action
- Adjunctive treatment of bacterial meningitis (starting before or with the first dose of antibacterial). Dexamethasone IV 8.3 mg every 6 hours for 4 days.
- Cerebral oedema: Initially Dexamethasone 8 to 16 mg for 1 dose, then (IM/IV) 5 mg every 6 hours until adequate response achieved then taper-off gradually
- Cerebral oedema (malignancy): Dexamethasone 0.5 - 10 mg PO / 24h
disorders : Dexamethasone 0.5 - 10 mg PO / 24h
- Diagnosing Cushing disease: Overnight dexamethasone suppression test. Dexamethasone 1 mg PO for 1 dose, to be given at night
- Anorexia in Palliative care: Dexamethasone 2-4 mg PO per day
- Nausea and vomiting and headache in palliative care. Dexamethasone 8 to 16 mg daily.
- CCF, Diabetes, Untreated infection, Hypertension
- Psychiatric disease, peptic ulcer
- Hypertension, Cushing syndrome, Adrenal suppression
- High blood glucose, Osteoporosis
- Acute psychiatric reactions and delirium
- raised WCC (specifically neutrophilia).