Hypokalaemia, hypernatraemia, or hypomagnesaemia increase the toxic cardiovascular effects of Digoxin because of their depressive effects on the Na+/K+ ATPase pump.
About : Always check the BNF link here
Mode of action
Indications/Loading Doses in Microgrammes 0.5 mg = 500 mcg
Interactions
Dose range:You must check with BNF or drug datasheet. Doses in Microgrammes 0.5 mg = 500 mcg
Name Starting Dose Frequency Route Digoxin (Loading dose Fast AF but well) 500 mcg at 0 and 6 hours (2nd dose can be 250 mcg if elderly) stat PO Digoxin (Emergency) 750 mcg to 1 g given slow IV over 2 hours stat IV infusion Digoxin (Maintenance) 125-250 mcg ( 62.5 mcg in frail elderly) OD PO Contraindications
Side effects
Toxicity more common with
References
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Digoxin
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