Be very cautious with combinations of these drugs
About: Always check the BNF link here
Drugs
Details
Opiates/Codeine Increased toxicity and sedation as well as constipation. Lower dose or avoid Benzodiazepines Increased toxicity and sedation. Lower dose or avoid Diuretics Can dehydrate and upset electrolytes - use cautiously. May worsen or precipitate AKI. Anticoagulants Can precipitate bleeding Antiplatelets Can precipitate bleeding NSAIDS Can precipitate bleeding, fluid retention and AKI Steroids Can precipitate infection and fluid retention Paracetamol Risks of Toxicity
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Drugs to avoid in Liver failure
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