Related Subjects: |Hypertension
About
- Used with combination therapy for refractory BP control
Mode of action
- Alpha - 1 blocker
Indications
- Hypertension - usually a second line agent
- Benign prostatic hypertrophy/hyperplasia
Dose
- Doxazosin 1 mg od increasing to 2 mg od after 1-2 weeks
- Standard dose Doxazosin 4 mg od but up to 16 mg od used
Interactions
- Hypotension with other antihypertensives
Contraindications
- Hypotension, Relative C/I in pregnancy, avoid with lactation
Side effects
- Breathlessness, cough, fatigue
- Anxiety, flu-like symptoms
- Rarely cholestasis, hepatitis