Makindo Medical Notes.com

Related Subjects: |Methylthioninium chloride (Methylene blue) |Drug Toxicity with Specific Antidotes |Methaemoglobinaemia

About: Always check the BNF link here

• Always give slow IV and also called Methylene blue
• Given when there are symptoms despite oxygen therapy
• Check BNF or equivalent for prescribing advice

Indication/Dose

• Drug- or chemical-induced methaemoglobinaemia: Child 3 months–17 years: Initially 1–2 mg/kg, then 1–2 mg/kg after 30–60 minutes if required, to be given over 5 minutes, seek advice from National Poisons Information Service if further repeat doses are required; maximum 7 mg/kg per course. Adult
• Drug- or chemical-induced methaemoglobinaemia:Initially 1–2 mg/kg, then 1–2 mg/kg after 30–60 minutes if required, to be given over 5 minutes, seek advice from National Poisons Information Service if further repeat doses are required; maximum 7 mg/kg per course.
• Aniline- or dapsone-induced methaemoglobinaemia: Child 3 months–17 years: Initially 1–2 mg/kg, then 1–2 mg/kg after 30–60 minutes if required, to be given over 5 minutes, seek advice from National Poisons Information Service if further repeat doses are required; maximum 4 mg/kg per course.
• Aniline- or dapsone-induced methaemoglobinaemia: Adult Initially 1–2 mg/kg, then 1–2 mg/kg after 30–60 minutes if required, to be given over 5 minutes, seek advice from National Poisons Information Service if further repeat doses are required; maximum 4 mg/kg per course.