Related Subjects:
|Lung Cancer
|Hypercalcaemia
|Oncological emergencies
|Malignant Hyperparathyroidism due to PTHrP
|Lambert-Eaton syndrome (LEMS)
|Superior Vena Caval Obstruction syndrome
|Syndrome of Inappropriate ADH (SIADH) secretion
If a patient is hypercalcaemic and has a raised PTHrP they have a 99% chance of having a malignancy (very specific). PTHrP at low levels is found normally and has more paracrine and autocrine functions in virtually all tissues than classical endocrine functions and is essential in embryonic, fetal and post-natal life.
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Malignant Hyperparathyroidism due to PTHrP
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