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Related Subjects: |Rheumatoid arthritis |Systemic Sclerosis (Scleroderma) |RA vs OA |Acute and Chronic Gout |Calcium Pyrophosphate Deposition (Pseudogout)
Comparing Rheumatoid and Osteoarthritis | |
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Osteoarthritis | Rheumatoid |
Degenerative | Autoimmune |
Cartilage loss | Inflamed synovium |
Morning stiffness < 30 mins | Morning stiffness > 60 mins |
Asymmetrical | Symmetrical |
Joints involved | Joints + Extra-articular manifestations |
Age onset 20-40 | Age onset > 50 |
Lack of systemic symptoms. Joint symptoms | Fatigue, low grade fever, malaise, rheumatoid nodules, sjogrens syndrome, felty's syndrome |
Movement worsens pain | Movement can ease pain |
PIP and DIP. Symmetrical Small and large joints | PIP and MCP and weight bearing joints - knees, hips, spine |
RF negative | RF positive high CRP ESR ANA positive Anti CCP |
Onset slow over years | Onset over weeks and months |
Joints enlarged, cool, hard on palpation | Joints are swollen, red, warm, tender, soft synovium |
Crepitus and reduced range of motion, joint malalignment | Synovitis, joint destruction |
Osteophytes and joint space narrowing on X Ray | Erosions on X ray |