Makindo Medical Notes.com |
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Cause | Diagnostic Tests | Management |
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Osteoarthritis |
- Clinical diagnosis based on joint pain and stiffness
- X-ray: Joint space narrowing, osteophytes, subchondral sclerosis |
- NSAIDs: For pain relief
- Physical therapy: To improve joint function - Joint replacement surgery: For severe cases |
Osteoporosis |
- Bone density scan (DEXA): To measure bone mineral density
- Serum calcium and vitamin D: To assess deficiencies |
- Bisphosphonates: To strengthen bones and reduce fracture risk
- Calcium and vitamin D supplementation: To support bone health - Weight-bearing exercises: To improve bone density |
Bone Metastases (Cancer) |
- Bone scan or PET scan: To detect bone metastasis
- Biopsy: To confirm cancer origin - CT/MRI: To evaluate the extent of disease |
- Radiotherapy: To reduce pain and control metastases
- Bisphosphonates or Denosumab: To prevent bone fractures - Pain management: Opioids and NSAIDs |
Osteomyelitis (Bone Infection) |
- Blood tests: Elevated white blood cells (WBC) and inflammatory markers (CRP, ESR)
- Bone biopsy: To identify causative organism - MRI/CT scan: To assess extent of infection |
- Antibiotics: Prolonged course based on culture results
- Surgical debridement: For removing necrotic bone - Follow-up imaging: To assess response to treatment |
Fractures |
- X-ray: To visualize fracture
- CT/MRI: For complex or occult fractures |
- Immobilization: Casts or splints
- Surgery: Open reduction and internal fixation (ORIF) for displaced fractures - Pain management: NSAIDs or opioids |
Paget's Disease of Bone |
- Serum alkaline phosphatase: Elevated in active disease
- X-ray: Cortical thickening, bone deformities - Bone scan: To identify affected areas |
- Bisphosphonates: To control bone turnover
- Calcitonin: As an alternative therapy - Pain management: NSAIDs or acetaminophen |
Multiple Myeloma |
- Serum/urine electrophoresis: Monoclonal protein (M protein)
- Bone marrow biopsy: To confirm diagnosis - Bone X-rays: "Punched-out" lytic lesions |
- Chemotherapy: For systemic control
- Bisphosphonates: To reduce bone damage - Stem cell transplantation: For eligible patients |
Fibromyalgia |
- Diagnosis based on widespread pain and tenderness at specific points
- Exclusion of other conditions through blood tests (e.g., thyroid function, ESR, CRP) |
- Exercise therapy: Low-impact aerobic exercises
- Antidepressants: Amitriptyline, duloxetine for pain and mood - Anticonvulsants: Pregabalin, gabapentin for pain relief |
Rheumatoid Arthritis |
- Rheumatoid factor (RF) and anti-CCP antibodies: Positive in most cases
- X-ray: Joint erosions and deformities - ESR and CRP: Elevated in active disease |
- DMARDs: Methotrexate, sulfasalazine to slow disease progression
- Biologics: TNF inhibitors for severe cases - NSAIDs and corticosteroids: For inflammation control |
Vitamin D Deficiency (Osteomalacia) |
- Serum 25(OH) vitamin D: Low levels
- Serum calcium and phosphate: May be low or normal - X-rays: Looser's zones (pseudofractures) |
- Vitamin D supplementation: Oral or IV vitamin D
- Calcium supplementation: If necessary - Sunlight exposure: To naturally increase vitamin D levels |