ABC Medical Notes.com

About: In prep

Aetiology

Clinical

• Cerebral venous sinus thrombosis: Persistent or severe headaches, seizures or focal neurology
• Splanchnic vein thrombosis
• Pulmonary embolism : Shortness of breath, persistent chest
• Arterial ischaemia : Swelling, redness, pallor or cold lower limbs
• Bleeding can be significant and unexpected.

Investigations

• If day 4-28 and platelets normal then VITT unlikely
• if platelets < 150 x 109 /L then send Dimer 1D Dimer as mcg/L, (includes FEU or DDU) = 2mg/L (cases -D Dimers > 4000 mcg/L but D Dimers 2000-4000 mcg/L need to be discussed as probable case) Does the patient have symptoms of another clinical condition that needs investigation If N then home with safety net advice to return if persistent or escalating symptoms or other concern for thrombosis for repeat testing If Y then further work up required for alternative diagnoses Send clotting (fibrinogen) and d-dimer tes

Pathology

Management

References

• Guidance